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       XXIII Annual Congress of the Iranian Society of Ophthalmology        بـیــست و سومین کنــگــره سـالیـانه انـجـمـن چـشـم پـزشـکی ایـــران
مقاله Abstract


Title: Effects of corneal collagen cross-linking on ocular aberrations and contrast sensitivity in patients with keratoconus
Author(s): Siamak Zarei-Ghanavati1; MD, FICO, Hamid Khakshoor1; MD, Amir-Hossein Vejdani2, MD
Presentation Type: Oral
Subject: Cornea and Anterior Segment
Others:
Presenting Author:
Name: Siamak Zarei ghanavati
Affiliation :(optional) Mashhad University of Medical Sciences
E mail: sizagh@yahoo.com
Phone: 0511-7659461
Mobile: 09151153024
Purpose:

To determine changes in higher –order aberrations (HOAs) and contrast sensitivity after collagen crosslinking (CXL).

Methods:

Twenty two eyes of eleven patients with keratoconus underwent CXL. Uncorrected distance visual acuity (UDVA),best spectacle–corrected visual acuity (BSCVA), contrast sensitivity test (Pelli Robson) and higher-order aberrations (ZyWave) before and 1, 3, 6 and 8 months after CXL, were measured.

Results:

The mean total HOA in 22 eyes of eleven patients with keratoconus underwent CXL, were measured 2.24, 2.34, 2.28, 2.17 and 2.03 micrometer in before and 1, 3, 6 and 8 months after CXL, respectively (p<0.01; except for 3rd month). Decreasing in other HOAs including vertical coma, horizontal coma, vertical trefoil, horizontal trefoil and Spherical Aberration observed in 6 and 8 months after CXL which except horizontal coma, all were significant (p<0.01). UCVA and BSCVA increased significantly in all months after CXL in proportion of before CXL (p<0.001). Although mean contrast sensitivity declined significantly, improved significantly in 3rd, 6th and 8th months (p<0.00001).

Conclusion:

CXL is not only efficacious in inhibiting the progression of keratoconus but also can improve contrast sensitivity and decrease HOAs except horizontal coma.

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  - بـیــست و سومین کنــگــره سـالیـانه انـجـمـن چـشـم پـزشـکی ایـــران