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مقاله
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Abstract
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Title:
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Effects of corneal collagen cross-linking on ocular aberrations and contrast sensitivity in patients with keratoconus
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Author(s):
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Siamak Zarei-Ghanavati1; MD, FICO, Hamid Khakshoor1; MD, Amir-Hossein Vejdani2, MD
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Siamak Zarei ghanavati
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Affiliation :(optional)
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Mashhad University of Medical Sciences
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E mail:
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sizagh@yahoo.com
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Phone:
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0511-7659461
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Mobile:
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09151153024
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Purpose:
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To determine changes in higher –order aberrations (HOAs) and contrast sensitivity after collagen crosslinking (CXL).
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Methods:
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Twenty two eyes of eleven patients with keratoconus underwent CXL. Uncorrected distance visual acuity (UDVA),best spectacle–corrected visual acuity (BSCVA), contrast sensitivity test (Pelli Robson) and higher-order aberrations (ZyWave) before and 1, 3, 6 and 8 months after CXL, were measured.
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Results:
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The mean total HOA in 22 eyes of eleven patients with keratoconus underwent CXL, were measured 2.24, 2.34, 2.28, 2.17 and 2.03 micrometer in before and 1, 3, 6 and 8 months after CXL, respectively (p<0.01; except for 3rd month). Decreasing in other HOAs including vertical coma, horizontal coma, vertical trefoil, horizontal trefoil and Spherical Aberration observed in 6 and 8 months after CXL which except horizontal coma, all were significant (p<0.01). UCVA and BSCVA increased significantly in all months after CXL in proportion of before CXL (p<0.001). Although mean contrast sensitivity declined significantly, improved significantly in 3rd, 6th and 8th months (p<0.00001).
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Conclusion:
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CXL is not only efficacious in inhibiting the progression of keratoconus but also can improve contrast sensitivity and decrease HOAs except horizontal coma.
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Attachment:
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