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مقاله
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Abstract
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Title:
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Corneal Endothelial Cell Changes Following Pars Plana Vitrectomy and Silicone Oil Injection in Phakic or Pseudophakic Eyes
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Author(s):
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Feraidoon Farrahi, MD; Mostafa Feghhi, MD; Farshad Ostadian, MD; Arash Alivand MD.
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Presentation Type:
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Oral
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Subject:
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Posterior Segment
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Others:
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Presenting Author:
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Name:
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Arash Alivand
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Affiliation :(optional)
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Ahvaz Jundishapur University of Medical Science
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E mail:
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arashal@hotmail.com
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Phone:
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06112228076
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Mobile:
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09173141792
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Purpose:
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To evaluate the effect of silicone oil (SO) on the corneal endothelium in phakic and pseudophakic vitrectomizied eyes.
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Methods:
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This prospective comparative case-control study evaluated the corneal endothelial characteristics in SO filled vitrectomizied eyes (case group 64 eyes) compared to the vitrectomizied eyes without SO injection (control group 46 eyes). The preoperative and postoperative endothelial cell densities (ECD), coefficient of variation (CV), and percentage of hexagonal cells (hexagonality) at the corneal center evaluated by non-contact specular microscopy were compared between two groups. Exclusion criteria was consist of aphakia, any degree of anterior chamber inflammation, SO bubbles in anterior chamber and increased intraocular pressure in postoperative period.
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Results:
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Six months after SO injection the mean ECD was 2438 ± 327/mm2 in the case group and 2463 ± 361/mm2 in the control group (P = 0.714). Six months after operation hexagonality in the case group was 49 ± 6.8 and in control group was 54.6 ± 8.9. This difference was statistically significant (P = 0.001).
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Conclusion:
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Although presence of SO in vitreous cavity of phakic or pseudophakic eyes cause slight reduction in number of endothelial cells but significant endothelial cell morphology changes occurs. Thus removal of SO after reaching the desired tamponade effect is recommended.
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Attachment:
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