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مقاله
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Abstract
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Title:
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Reproducibility of retinal nerve fiber layer thickness measurements with specteral domain Cirrus OCT in glaucomatous eyes
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Author(s):
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Reza soltani moghadam,MD .Yousef Alizadeh,MD . Mohamad Javad Mohamadi,MD. Mohamadreza Panjtan Panah, MD. Mohamadreza Absari Haghighi,Ehsan Kazemnejad
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Presentation Type:
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Oral
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Subject:
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Glaucoma
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Others:
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Presenting Author:
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Name:
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Reza Soltani moghaddam
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Affiliation :(optional)
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Guilan university of medical sciences, Eye research center
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E mail:
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Reza_sm76@yahoo.com
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Phone:
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02614426908
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Mobile:
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09123602196
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Purpose:
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To assess the reproducibility of spectral domain Cirrus high-definition optical coherence tomography (HD-OCT; Carl Zeiss Meditec, Dublin, CA, USA) for analysis of peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous eyes
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Methods:
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Fourty five eyes (one eye from each glaucomatos patient) were imaged with Cirrus HD-OCT. Each eye was imaged three times by two separate operators. Intraclass correlation coefficient (ICC), coefficient of variation (COV), and test–retest variability were evaluated for both intraobserver and interobsever measurements
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Results:
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In intraobserver measurements, the average thickness ICC was 0.983. CV and test–retest variability were 2.3% and 4.4 µ respectively. In quadrants ICC ranged from 0.886 to 0.956, the lowest associated with nasal quadrant and CV ranged from 3.6 to 7.7%. In interobsever measurements, the average thickness ICC was 0.979. CV and test–retest variability were 2.4% and 4.5 µ respectively. In quadrants ICC ranged from 0.886 to 0.957, the lowest associated with nasal quadrant and CV ranged from 3.8 to 8.6%
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Conclusion:
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The reproducibility of Cirrus OCT for RNFL thickness is sufficiently good to be useful clinically as a measure of glaucoma progression
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Attachment:
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