|
مقاله
|
Abstract
|
|
|
Title:
|
Ocular Myasthenia gravis (MG)
|
Author(s):
|
Esmaeil Rezaeian
|
Presentation Type:
|
Poster
|
Subject:
|
Strabismus & Neuro-ophthalmology
|
Others:
|
|
Presenting Author:
|
|
Name:
|
Esmaeil Rezaeian
|
Affiliation :(optional)
|
|
E mail:
|
dr.rezaeian@gmail.com
|
Phone:
|
08652340501
|
Mobile:
|
09123575311
|
|
|
Purpose:
|
case report
|
Methods:
|
case report
|
Results:
|
A 47 years old lady who presented with 3 weeks history of diplopia, headache and right eye ptosis. She had a history of fluctuating and variable diplopia for the last two years.
Best corrected visual acuity in both eyes was 6/6, anterior and posterior segment examination was unremarkable. There was evidence of right mild ptosis and diplopia in the primary gaze left lateral gaze and inferior gazes and confirmed on binocular single vision test, Coagan’s lid twitch was positive. CT scan and all blood investigation was unremarkable. Tensilon test showed markedly increase in interpulpebral fissure after 3 minutes.
|
Conclusion:
|
Myasthenia gravis (MG) is a disorder of neuromuscular transmission junction characterized by weakness and fatigability of skeletal muscles. The basic pathology is a reduced number of acetylcholine receptors (AChR) at the postsynaptic muscle membrane brought about by an acquired autoimmune reaction producing anti-AChR antibodies. Two major clinical forms of MG are distinguished, ocular MG and generalized MG.Women are affected more than men with a female-to-male ratio of 3:2. but Ocular MG shows a male preponderance. MG can occur at any age but peaks in females in the fourth to fifth decade of life and in males in the sixth to seventh decade.
|
Attachment:
|
597ocular MG.pptx
|
|