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مقاله
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Abstract
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Title:
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Oxygen therapy for corneal edema after cataract surgery: A randomized clinical trial
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Author(s):
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Farideh Sharifipour, MD; Mahmodreza Panahibazaz, MD; Esmaeil Idani, MD; Maryam Hajizadeh, MD; Azadeh Saki, PhD
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Farideh Sharifipour
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Affiliation :(optional)
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Department of Ophthalmology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
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E mail:
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sharifipourf@yahoo.com
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Phone:
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4440063
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Mobile:
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09161117223
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Purpose:
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To evaluate the effects of systemic and transcorneal oxygen on corneal edema after cataract surgery.
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Methods:
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Forty five patients with severe corneal edema after cataract surgery were randomized into 3 groups: Group 1 received medical therapy; Group 2 received medication and transcorneal oxygen at a flow rate of 5 L/min for 1 hour twice daily for 3 weeks; and Group 3 received medication and systemic normobaric oxygen by face mask at a flow rate of 10 L/min for 1 hour twice daily for 3 weeks. Pachmetry and specular microscopy were performed before, 1, 3 and 12 months after surgery.
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Results:
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Preoperatively, the groups were matched in all parameters. Central corneal thickness was>1000µ after surgery in all groups. Preoperative values were restored in 30, 14, and 30 days in groups 1, 2, and 3, respectively. (P=0.002) At the end of the study, endothelial cell count was 1625, 1906, 1720 (P=0.222, ANOVA) with endothelial cell loss of 37%, 25%, and 32% in groups 1, 2, and 3, respectively. (P=0.244, ANOVA) One patient in groups 1 and 3 developed bullous keratopathy.
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Conclusion:
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Transcorneal oxygen therapy decreases corneal edema after cataract surgery more rapidly than conventional therapy and systemic oxygen therapy.
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Attachment:
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