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مقاله
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Abstract
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Title:
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Study of the relation between tear film osmolarity and diabetes
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Author(s):
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Dr. Akbar Derakhshan,Dr. Majid Abrishami,Dr. Arash Omidtabrizi
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Akbar Derakhshan
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Affiliation :(optional)
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cornea research center, Mashhad University of Medical Sciences
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E mail:
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derakhshana@mums.ac.ir
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Phone:
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8401136
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Mobile:
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09155204131
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Purpose:
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Tear osmolarity measurement has proven to be a sensitive test for dry eye diagnosis and it’s results confirms the results of schirmer and tear-film break-up time tests. Tears osmolarity test has not been compared between diabetic patients and normal population.
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Methods:
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fifty diabetic patients and twenty healthy individuals as control group participated in study according to inclusion and exclusion criteria. Complete eye examination including ophthalmoscopy, basic tear secretion(schirmer) tear-film break-up time (TBUT) and tear osmolarity test with tearlab osmometer were performed for both study and control groups. HbA1c was checked
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Results:
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Mean tear osmolarity was 294mosmol/L in study group and 291.4msomol/L in control group and the difference wasn’t significant(P=0.456). There was no sex or age privilege in tear osmolarity among patients (P>0.05). There was no significant relation between duration of diabetes, stage of diabetic retinopathy and mean TBUT with tear osmolarity (p>0.05). schirmer test results and HbA1c were significantly related to the tear osmolarity (P=0.004 for both).
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Conclusion:
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Just suffering from diabetes, is not a reason for a higher than normal tear osmolarity. But the poorer the blood sugar is controlled, the higher tear osmolarity and risk of dry eye symptoms. Tear osmolarity test results are compatible with basic tear secretion (schirmer) test.
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Attachment:
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