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مقاله
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Abstract
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Title:
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Clinical Features of Posner-Schlossman Syndrome in a Non-endemic Area: Possible Etiologic Role of Cytomegalovirus Infection
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Author(s):
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Alireza Hedayatfar M.D., Soon-Phaik Chee FRCS(G) , FRCOphth
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Presentation Type:
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Oral
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Subject:
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Glaucoma
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Others:
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Presenting Author:
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Name:
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Alireza Hedayatfar
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Affiliation :(optional)
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Noor Ophthalmic Research Center
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E mail:
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ahedayatfar@norc.ac.ir
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Phone:
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021-82400
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Mobile:
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09126064677
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Purpose:
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To describe clinical features, treatment and course of disease in four patients diagnosed with Posner-Schlossman Syndrome (PSS) who had evidence of cytomegalovirus (CMV) infection in their aqueous humour.
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Methods:
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Review of 4 consecutive CMV positive PSS patients seen at the Noor Eye Hospital. CMV was diagnosed by polymerase chain reaction (PCR) analysis of their aqueous. Demographic data, clinical findings, endothelial cell count and disease course were collected.
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Results:
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All 4 patients were immunocompetent males. Mean age of onset was 44.5 years (range, 32–63 years). Maximum intraocular pressure ranged from 36 to 48 mmHg. Mild to moderate anterior chamber reaction, lack of posterior synechiae and posterior segment involvement were consistent features in all the patients. Three patients had diffuse iris atrophy. One patient with a stromal immune ring at presentation developed features of Fuch’s Heterochromic Iridocyclitis (FHI) later in his course of disease. Heterochromia was also observed in another patient. All patients had a positive titre of IgG but not IgM against CMV, and none had concomitant CMV antigenemia.
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Conclusion:
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In our population, PSS may be associated with CMV infection and may develop clinical features similar to FHI.
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Attachment:
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