To report the anatomical as well as visual outcomes of double layered amniotic membrane transplantation (AMT) in patients with advanced Pseudomonas eratitis leading to Descemetocele formation

Double layered amniotic membrane transplantation was performed in 6 eyes of 6 female patients with pseudomonas keratitis caused by cosmetic lens infection referred to Farabi Eye Hospital, Tehran University of Medical Sciences. They underwent surgery after not responding to application of pseudomonas species sensitive antibiotic with a severe thinning and corneal Descemetocele. All the patients underwent complete examination preoperatively, and examination, corneal optical coherence tomography (OCT) and pachymetry or orbscan after operation. The mean follow up period was 24+/_ 2 months

There was no corneal perforation and none of the patients needed emergency corneal transplantation. All the patients had visual acuity of hand motion before operation which improved to 20/50 to 20/30 3 months after surgery. No surgical or post operative complication occurred in this series.

Double layered amniotic membrane transplantation can result in acceptable anatomical and visual outcomes in patients with advanced Pseudomonas Keratitis leading to Descemetocele formation and exempts them from emergent corneal transplantation.