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مقاله
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Abstract
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Title:
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Comparison between Accelerated and Standard CXL: A Randomized Clinical Trial
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Author(s):
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Hahsemi H, Asgari S
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Hassan Hashemi
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Affiliation :(optional)
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Noor ophthalmology research center, Noor Eye Hospital, Tehran, Iran
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E mail:
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info@irsocongress.org
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Phone:
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0
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Mobile:
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09121127421
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Purpose:
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Comparison of the visual acuity and quality between accelerated and standard CXL in the treatment of keratoconus
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Methods:
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This randomized clinical trial was performed on 60 keratoconic eyes (30 eyes in each group) and the 6-month results of accelerated CXL (18mW/cm2, 5min) and standard CXL (3mW/cm2, 30min) were compared.
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Results:
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The mean changes of UCVA (P=0.784), BCVA (P=0.451), and MRSE (P=0.514) and the mean decrease of max- K (P=0.147) and min- K (P=0.330) did not differ significantly between the two groups. The mean corneal thickness decrease was more in the 30-minute group versus the 5-minute group (P=0.024). The mean decrease of corneal hysteresis (P=0.348) and corneal resistance factor (P=1.000) was similar and the mean decrease of the endothelial cell count did not show a significant difference (P=0.218) between the two groups. The trend of the changes of the above-mentioned indices was not significant in the two groups, except for the decreasing trends of CCT and ECC.
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Conclusion:
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Based on the 6-month results, visual acuity and quality of accelerated and standard CXL are similar. This study will continue to report the long-term comparative results of the two methods.
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Attachment:
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