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مقاله
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Abstract
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Title:
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Cornea haziness and outcome after collagen crosslinking (CXL) for keratoconus: a comparison between total epithelium off and partial epithelial removal methods
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Author(s):
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Alireza Peyman, MD, Behrooz Rahimi, MD, Hasan Razmjoo, MD, Mohamadreza Peyman, MD
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Alireza Peyman
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Affiliation :(optional)
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Assistant professor, Isfahan University of Medical Sciences, Isfahan, Iran
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E mail:
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drpeyman@hotmail.com
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Phone:
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03116617302
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Mobile:
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09133271149
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Purpose:
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to determine outcome after CXL with total epithelium removal and partial epithelium removal methods.
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Methods:
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44 keratoconic eyes enrolled. In the first group we totally removed the corneal epithelium with a diameter of 9mm, in the second group the central 3mm of epithelium kept undamaged and removal was performed by removing a 3-mm width ring. UV crosslinking performed in both groups. Examination was performed before and 6 months after the surgery regarding corrected vision, quantitative optical cornea haziness, keratoconus indices, and refraction.
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Results:
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The difference between two groups was not significant regarding post-op corneal haziness, refraction, and visual acuity (p>0.05). However, comparison of pre and post-operative parameters within each group revealed that total removal of the cornea has resulted in significant improvement of K-max (p-value: 0.01), and Q-value (p-value: 0.009); while eyes in partial removal group had better improvement of corrected vision (p-value: 0.006). Both methods had significant and similar increase in optical corneal density (p-value<0.0001).
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Conclusion:
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In our study keeping central corneal epithelium intact was not beneficial for decreasing corneal haziness but this method caused better improvement in corrected vision. Total epithelium off technique resulted in better improvement of Kmax and Q value.
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Attachment:
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