To evaluate the feasibility and efficacy of Femtosecond laser-assisted suture less Anterior Lamellar Keratoplasty (FALK) with fibrin glue in patients with anterior corneal opacities.

Patients with decreased vision due to corneal opacity and scar depth less than 250µm and residual stromal bed >250µm were included in this study.

Seven patients were included in this study. Follow up ranged from 4 months to 18 months (mean=13.9 months). Femtosecond laser could be successfully used to create the lamellar cut and trephination in both in the recipient and donor bed. The mean UCVA improved from 0.24 Log MAR preoperatively to 0.19 log MAR postoperatively (p-value=0.28). The preoperative BCVA was 0.29 log MAR, which significantly improved to 0.75 log MAR, postoperatively (p-value=0.04).Complications included: one case with significant residual corneal residual stromal scar and epithelial ingrowths in one case, mild residual stromal haze in 4 patients (57%), transient dry eye in 2 patients (28%) and irregularity of the corneal surface in topography in 4 patients (0.57%).

Femtosecond laser-assisted suture less anterior lamellar keratoplasty (FALK) with fibrin glue is a safe and effective procedure in properly selected cases with anterior corneal opacities.