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مقاله
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Abstract
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Title:
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Cornea collagen crosslinking for keratoconus: a comparison between accelerated and conventional methods
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Author(s):
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Hasan Razmjoo, MD, Alireza Peyman, MD, Ali Rahimi, MD
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Hasan Razmju
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Affiliation :(optional)
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Professor, Isfahan University of Medical Sciences, Isfahan, Iran
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E mail:
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dr_razmjoo@yahoo.com
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Phone:
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Mobile:
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09131180292
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Purpose:
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Evaluating collagen crosslinking (CXL) for keratoconus with accelerated 5 minutes UV and conventional 30 minutes exposure
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Methods:
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40 eyes randomized to accelerated and conventional CXL groups. Accelerated group irradiated with18 mW/cm2 UVA for 5 minutes, and conventional group 30 minutes of 3 mW/cm2. 12 months after CXL subjects evaluated regarding corrected acuity, refraction, topography, and endothelial cell count (ECC).
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Results:
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LogMar corrected acuity before intervention was 0.21 +/- 0.16 and 0.36 +/- 0.28 which changed to 0.18 +/- 0.17 and 0.25 +/- 0.18 for conventional and accelerated groups (p>0.05). Surgically induced astigmatism was 0.99 +/- 0.83 and 1.23 +/- 1.13 diopters in conventional and accelerated groups (p: 0.45). Hyperopic shift was 0.5 and 0.42 diopter in conventional and accelerated groups. Pre-op Kmax was 52.7 +/- 5.66 and 56.3 +/- 7.06 that changed to 52.1 +/- 5.37 and 56.3 +/- 7.75 diopters in conventional and accelerated groups (p>0.05). ECC was 2674.25 +/- 170.3 and 2752.80 +/- 214.5 before CXL, and 2672.55 +/- 168.1 and 2727.35 +/- 190.3 after CXL in conventional and accelerated groups (p>0.05).
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Conclusion:
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Two methods of conventional 30 minutes UV exposure and accelerated 5 minutes irradiation for CXL are equal according to our results.
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Attachment:
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